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| 2022 Grapefruit League Spring Training Schedule |
The day by day schedule for the Grapefruit League in 2022. All times are local (Florida).
Note: Due to the lockout that delayed spring training, a shortened schedule was necessary and released on March 11.
| Thursday, March 17 |
| Game | Time | Stadium | Location | Crowd |
| Red Sox 14, Twins 1 | 1:05 | JetBlue Park | Fort Myers | 8,303 |
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| Friday, March 18 |
| Game | Time | Stadium | Location | Crowd |
| Pirates 4, Yankees 3 | 1:05 | LECOM Park | Bradenton | 4,565 |
| Red Sox 7, Rays 6 | 1:05 | JetBlue Park | Fort Myers | 7,819 |
| Cardinals 4, Astros 2 | 1:05 | Roger Dean Stadium | Jupiter | 5,007 |
| Phillies 6, Tigers 6 | 1:05 | Joker Marchant Stadium | Lakeland | 6,258 |
| Braves 3, Twins 1 | 1:05 | CoolToday Park | North Port | 4,875 |
| Blue Jays 9, Orioles 5 | 1:05 | Ed Smith Stadium | Sarasota | 5,096 |
| Marlins 8, Nationals 3 | 6:05 | Ballpark Palm Beaches | W Palm Beach | 2,436 |
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| Saturday, March 19 |
| Game | Time | Stadium | Location | Crowd |
| Pirates 6, Tigers 3 | 1:05 | LECOM Park | Bradenton | 3,667 |
| Phillies 3, Blue Jays 2 | 1:05 | BayCare Ballpark | Clearwater | 8,646 |
| Red Sox 1, Twins 0 | 1:05 | Hammond Stadium | Fort Myers | 7,761 |
| Marlins 10, Astros 2 | 1:05 | Roger Dean Stadium | Jupiter | 3,173 |
| Braves 4, Rays 4 | 1:05 | Charlotte Sports Park | Port Charlotte | 3,638 |
| Yankees 3, Orioles 3 | 1:05 | Ed Smith Stadium | Sarasota | 5,914 |
| Mets 6, Nationals 2 | 6:05 | Ballpark Palm Beaches | W Palm Beach | 3,861 |
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| Sunday, March 20 |
| Game | Time | Stadium | Location | Crowd |
| Twins 3, Rays 0 | 1:05 | Hammond Stadium | Fort Myers | 3,724 |
| Red Sox 3, Orioles 2 | 1:05 | JetBlue Park | Fort Myers | 7,910 |
| Braves 5, Phillies 1 | 1:05 | CoolToday Park | North Port | 5,475 |
| Tigers 8, Yankees 7 | 1:05 | Steinbrenner Field | Tampa | 9,502 |
| Nationals 3, Astros 2 | 1:05 | Ballpark Palm Beaches | W Palm Beach | 2,792 |
| Blue Jays 10, Pirates 4 | 1:07 | TD Ballpark | Dunedin | 4,827 |
| Cardinals 6, Mets 4 | 1:10 | Clover Park | Port St. Lucie | 6,678 |
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| Monday, March 21 |
| Game | Time | Stadium | Location | Crowd |
| Red Sox 5, Braves 0 | 1:05 | JetBlue Park | Fort Myers | 6,490 |
| Marlins 3, Mets 0 | 1:05 | Roger Dean Stadium | Jupiter | 3,015 |
| Blue Jays 3, Tigers 1 | 1:05 | Joker Marchant Stadium | Lakeland | 4,177 |
| Pirates 5, Rays 1 | 1:05 | Charlotte Sports Park | Port Charlotte | 1,910 |
| Orioles 10, Twins 8 | 1:05 | Ed Smith Stadium | Sarasota | 3,754 |
| Yankees 5, Phillies 2 | 1:05 | Steinbrenner Field | Tampa | 6,587 |
| Cardinals 7, Nationals 3 | 6:05 | Ballpark Palm Beaches | W Palm Beach | 3,167 |
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| Tuesday, March 22 |
| Game | Time | Stadium | Location | Crowd |
| Orioles 10, Pirates 9 | 1:05 | LECOM Park | Bradenton | 2,498 |
| Phillies 7, Tigers 2 | 1:05 | BayCare Ballpark | Clearwater | 5,650 |
| Braves 4, Twins 0 | 1:05 | Hammond Stadium | Fort Myers | 6,329 |
| Cardinals 4, Marlins 3 | 1:05 | Roger Dean Stadium | Jupiter | 4,311 |
| Red Sox 4, Rays 2 | 1:05 | Charlotte Sports Park | Port Charlotte | 2,705 |
| Blue Jays 9, Yankees 2 | 1:07 | TD Ballpark | Dunedin | 3,672 |
| Mets 2, Astros 0 | 6:10 | Clover Park | Port St. Lucie | 4,967 |
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| Wednesday, March 23 |
| Game | Time | Stadium | Location | Crowd |
| Phillies 8, Blue Jays 7 | 1:05 | BayCare Ballpark | Clearwater | 5,091 |
| Twins 10, Red Sox 4 | 1:05 | JetBlue Park | Fort Myers | 7,281 |
| Marlins 3, Nationals 2 | 1:05 | Roger Dean Stadium | Jupiter | 1,608 |
| Pirates 6, Tigers 6 | 1:05 | Joker Marchant Stadium | Lakeland | 3,600 |
| Rays 7, Braves 7 | 1:05 | CoolToday Park | North Port | 4,602 |
| Astros 10, Cardinals 3 | 1:05 | Ballpark Palm Beaches | W Palm Beach | 2,649 |
| Yankees 7, Orioles 1 | 6:35 | Steinbrenner Field | Tampa | 5,612 |
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| Thursday, March 24 |
| Game | Time | Stadium | Location | Crowd |
| Phillies 3, Pirates 3 | 1:05 | LECOM Park | Bradenton | 2,600 |
| Twins 7, Rays 1 | 1:05 | Hammond Stadium | Fort Myers | 3,691 |
| Tigers 5, Yankees 3 | 1:05 | Joker Marchant Stadium | Lakeland | 3,217 |
| Braves at Blue Jays | 1:07 | TD Ballpark | Dunedin | PPD |
| Orioles 8, Red Sox 5 | 6:05 | Ed Smith Stadium | Sarasota | 4,702 |
| Astros 10, Nationals 8 | 6:05 | Ballpark Palm Beaches | W Palm Beach | 2,167 |
| Mets 9, Marlins 3 | 6:10 | Clover Park | Port St. Lucie | 3,308 |
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| Friday, March 25 |
| Game | Time | Stadium | Location | Crowd |
| Pirates 2, Twins 1 | 1:05 | LECOM Park | Bradenton | 3,148 |
| Phillies 6, Yankees 5 | 1:05 | BayCare Ballpark | Clearwater | 6,752 |
| Cardinals 5, Nationals 4 | 1:05 | Roger Dean Stadium | Jupiter | 4,465 |
| Braves 6, Red Sox 3 | 1:05 | CoolToday Park | North Port | 5,220 |
| Rays 9, Orioles 4 | 1:05 | Charlotte Sports Park | Port Charlotte | 2,210 |
| Tigers 8, Blue Jays 4 | 1:07 | TD Ballpark | Dunedin | 3,542 |
| Astros 2, Mets 1 | 6:05 | Ballpark Palm Beaches | W Palm Beach | 3,398 |
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| Saturday, March 26 |
| Game | Time | Stadium | Location | Crowd |
| Red Sox 5, Rays 3 | 1:05 | JetBlue Park | Fort Myers | 9,154 |
| Marlins 9, Cardinals 2 | 1:05 | Roger Dean Stadium | Jupiter | 4,682 |
| Tigers 14, Phillies 8 | 1:05 | Joker Marchant Stadium | Lakeland | 5,760 |
| Braves 8, Twins 6 | 1:05 | CoolToday Park | North Port | 5,090 |
| Blue Jays 10, Yankees 9 | 1:05 | Steinbrenner Field | Tampa | 8,038 |
| Mets 4, Nationals 2 | 1:10 | Clover Park | Port St. Lucie | 5,662 |
| Orioles 14, Pirates 5 | 6:05 | Ed Smith Stadium | Sarasota | 5,367 |
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| Sunday, March 27 |
| Game | Time | Stadium | Location | Crowd |
| Twins 6, Red Sox 3 | 1:05 | Hammond Stadium | Fort Myers | 8,534 |
| Astros 4, Marlins 3 | 1:05 | Roger Dean Stadium | Jupiter | 3,942 |
| Rays 4, Braves 1 | 1:05 | Charlotte Sports Park | Port Charlotte | 4,102 |
| Orioles 5, Tigers 4 | 1:05 | Ed Smith Stadium | Sarasota | 5,500 |
| Yankees 7, Pirates 4 | 1:05 | Steinbrenner Field | Tampa | 6,827 |
| Phillies 10, Blue Jays 5 | 1:07 | TD Ballpark | Dunedin | 5,597 |
| Mets 7, Cardinals 3 | 1:10 | Clover Park | Port St. Lucie | 7,205 |
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| Monday, March 28 |
| Game | Time | Stadium | Location | Crowd |
| Phillies 7, Orioles 1 | 1:05 | BayCare Ballpark | Clearwater | 4,663 |
| Astros 2, Cardinals 1 | 1:05 | Roger Dean Stadium | Jupiter | 3,176 |
| Yankees 11, Tigers 7 | 1:05 | Joker Marchant Stadium | Lakeland | 7,495 |
| Braves 5, Blue Jays 4 | 1:05 | CoolToday Park | North Port | 4,786 |
| Marlins 8, Nationals 1 | 1:05 | Ballpark Palm Beaches | W Palm Beach | 1,654 |
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| Tuesday, March 29 |
| Game | Time | Stadium | Location | Crowd |
| Pirates 6, Red Sox 2 | 1:05 | LECOM Park | Bradenton | 4,193 |
| Rays 4, Twins 2 | 1:05 | Charlotte Sports Park | Port Charlotte | 2,250 |
| Yankees 14, Phillies 2 | 1:05 | Steinbrenner Field | Tampa | 6,630 |
| Astros 3, Nationals 1 | 1:05 | Ballpark Palm Beaches | W Palm Beach | 1,794 |
| Mets 10, Marlins 0 | 6:40 | Roger Dean Stadium | Jupiter | 3,418 |
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| Wednesday, March 30 |
| Game | Time | Stadium | Location | Crowd |
| Tigers 7, Phillies 1 | 1:05 | BayCare Ballpark | Clearwater | 3,415 |
| Twins 9, Pirates 4 | 1:05 | Hammond Stadium | Fort Myers | 3,565 |
| Red Sox 10, Braves 7 | 1:05 | JetBlue Park | Fort Myers | 6,759 |
| Orioles 7, Rays 6 | 1:05 | Ed Smith Stadium | Sarasota | 2,734 |
| Cardinals 29, Nationals 8 | 1:05 | Ballpark Palm Beaches | W Palm Beach | 1,964 |
| Astros 5, Mets 3 (10) | 6:10 | Clover Park | Port St. Lucie | 4,149 |
| Blue Jays 11, Yankees 3 | 6:35 | Steinbrenner Field | Tampa | 6,225 |
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| Thursday, March 31 |
| Game | Time | Stadium | Location | Crowd |
| Orioles 4, Pirates 4 | 1:05 | LECOM Park | Bradenton | 2,143 |
| Phillies 5, Yankees 3 | 1:05 | BayCare Ballpark | Clearwater | 3,688 |
| Red Sox 4, Twins 3 | 1:05 | JetBlue Park | Fort Myers | 5,916 |
| Rays 5, Braves 1 | 1:05 | CoolToday Park | North Port | 4,439 |
| Blue Jays 5, Tigers 3 | 1:07 | TD Ballpark | Dunedin | 2,593 |
| Nationals 7, Mets 3 | 6:10 | Clover Park | Port St. Lucie | 3,987 |
| Marlins 7, Cardinals 4 | 6:40 | Roger Dean Stadium | Jupiter | 2,736 |
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| Friday, April 1 |
| Game | Time | Stadium | Location | Crowd |
| Blue Jays 6, Pirates 6 | 1:05 | LECOM Park | Bradenton | 2,581 |
| Twins 8, Braves 7 | 1:05 | Hammond Stadium | Fort Myers | 3,398 |
| Cardinals 7, Mets 2 | 1:05 | Roger Dean Stadium | Jupiter | 3,841 |
| Yankees 6, Tigers 2 | 1:05 | Joker Marchant Stadium | Lakeland | 4,330 |
| Rays 9, Red Sox 3 | 1:05 | Charlotte Sports Park | Port Charlotte | 2,364 |
| Orioles 3, Phillies 2 | 1:05 | Ed Smith Stadium | Sarasota | 2,866 |
| Astros 2, Marlins 1 | 1:05 | Ballpark Palm Beaches | W Palm Beach | 1,559 |
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| Saturday, April 2 |
| Game | Time | Stadium | Location | Crowd |
| Pirates 7, Red Sox 2 | 1:05 | JetBlue Park | Fort Myers | 7,004 |
| Orioles 2, Tigers 0 | 1:05 | Joker Marchant Stadium | Lakeland | 3,494 |
| Twins 8, Rays 2 | 1:05 | Charlotte Sports Park | Port Charlotte | 2,867 |
| Yankees 10, Braves 0 | 1:05 | Steinbrenner Field | Tampa | 7,507 |
| Phillies 2, Blue Jays 2 | 1:07 | TD Ballpark | Dunedin | 2,306 |
| Cardinals at Astros | 6:05 | Ballpark Palm Beaches | W Palm Beach | PPD |
| Nationals at Marlins | 6:40 | Roger Dean Stadium | Jupiter | PPD |
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| Sunday, April 3 |
| Game | Time | Stadium | Location | Crowd |
| Rays 9, Pirates 2 | 1:05 | LECOM Park | Bradenton | 5,343 |
| Phillies 8, Tigers 7 | 1:05 | BayCare Ballpark | Clearwater | 5,489 |
| Twins 8, Orioles 2 | 1:05 | Hammond Stadium | Fort Myers | 3,936 |
| Red Sox 6, Braves 3 | 1:05 | CoolToday Park | North Port | 6,340 |
| Nationals 9, Astros 6 | 1:05 | Ballpark Palm Beaches | W Palm Beach | 2,692 |
| Blue Jays 7, Yankees 5 | 1:07 | TD Ballpark | Dunedin | 5,627 |
| Mets 8, Marlins 4 | 1:10 | Clover Park | Port St. Lucie | 5,983 |
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| Monday, April 4 |
| Game | Time | Stadium | Location | Crowd |
| Mets 3, Astros 3 | 12:05 | Ballpark Palm Beaches | W Palm Beach | 1,963 |
| Twins 2, Red Sox 0 | 1:05 | Hammond Stadium | Fort Myers | 4,117 |
| Cardinals 4, Nationals 3 | 1:05 | Roger Dean Stadium | Jupiter | 2,535 |
| Tigers 4, Blue Jays 2 | 1:05 | Joker Marchant Stadium | Lakeland | 3,827 |
| Braves 8, Rays 2 | 1:05 | Charlotte Sports Park | Port Charlotte | 2,104 |
| Pirates 9, Orioles 3 | 1:05 | Ed Smith Stadium | Sarasota | 2,418 |
| Yankees 5, Phillies 2 | 1:05 | Steinbrenner Field | Tampa | 5,326 |
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| Tuesday, April 5 |
| Game | Time | Stadium | Location | Crowd |
| Cardinals at Marlins | 11:05 | Roger Dean Stadium | Jupiter | |
| Pirates at Phillies | 12:05 | BayCare Ballpark | Clearwater | |
| Mets at Nationals | 12:05 | Ballpark Palm Beaches | W Palm Beach | |
| Twins at Red Sox | 1:05 | JetBlue Park | Fort Myers | |
| Rays at Braves | 1:05 | CoolToday Park | North Port | |
| Tigers at Yankees | 1:05 | Steinbrenner Field | Tampa | |
| Orioles at Blue Jays | 1:07 | TD Ballpark | Dunedin | |
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| Wednesday, April 6 |
| Game | Time | Stadium | Location | TicketNetwork |
| Phillies at Rays | 12:35 | Tropicana Field | St. Petersburg | Tickets |
| Orioles at Tigers | 1:05 | Joker Marchant Stadium | Lakeland | Tickets |
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